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Other Intermediate of APIs

S.No Product Name Intermediate CAS No Therapeutic Use
1 Aripiprazole 7-hydroxy-3,4-dihydroquinolin-2-one 22246-18-0 Antipsychotic
7-(4-Bromobutoxy)-3,4-dihydroquinolin -2-one 129722-34-5
1-(2,3- Dichloro phenyl) pipearzine hydrochloride 119532-26-2
2 - α-(-4-Chlorophenyl) pyridine -2-methanol 27652-89-7 -
4-Hydroxypiperidine 5382-16-1
3 Brigatinib 1-methyl-4-(piperidin-4-yl)-piperazine  53617-36-0 small-molecule targetd cancer therapy
4 Crizotinib N-Boc-4-hydroxy piperidine 109384-19-2 Antineoplastic
5 Dabigatran Etexilate Mesylate 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester 211915-84-3 Antithrombotic
N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine ethyl ester 429658-95-7
Ethyl 3-(((2-(((4-((((hexyloxy) carbonyl) amino) iminomethyl) phenyl) amino)\methyl)-1-methyl-1H-benzimidazol-5-yl)\carbonyl)(pyridin-2-yl)amino) propanoate 211915-06-9
6 Domperidone 1-(3-Chloropropyl)-1,3-dihydro-1H-benzimidazol-2-one 62780-89-6 Antiemetic
5-Chloro 1,3 dihydro -1- (4-piperidinyl) -2H- benzimidazol - 2 -one 53786-28-0
7 Donepezil 4-[(5,6-Dimethoxy-1-indanon-2-yl) methyl] piperidine 120014-30-4 Nootropic
5,6-dimethoxy-2-(pyridine-4-yl)-methylene-indan-1-one 4803-74-1
8 Eprosartan 2-Butyl-4-formalimidazole 68282-49-5 Antihypertensive
9 Febuxostat Ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate 161797-99-5 Antihyperuricemic
Ethyl 2-(3-formyl-4-hydroxypheip)-4-methylthiazole-5-carboxylate 161798-01-2
Ethyl 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate  161798-02-3
Ethyl-2-(3-Formyl-4-isobutoxy phenyl)-4-methyl-1,3-thiazole-5-carboxylate 161798-03-4
Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate  160844-75-7
9 Golvatinib & Gilteritinib 1-N-Methyl-4-(4-piperidin-4-yl)-piperazine 53617-36-0 Anticancer
10 Linagliptin (R)-3-(boc-amino) piperidine 309956-78-3 Antidiabetic
(R)-3-Piperidinamine dihydrochloride 334618-23-4
11 Loperamide HCl 4-(4-Chlorophenyl)-4-hydroxy piperidine 39512-49-7 Antidiarrheal
N,N-Dimethyl(tera hydro-3,3-diphenyl)-2-furyliden ammonium bromide ( furanuminium bromide ) 37743-18-3
1,1-Diphenyl-3-butyrolactone 956-89-8
4-Bromo-2-2-diphenylbutyric acid 37742-98-6
12 Loratadine 3-[2-(3Chlorophenyl) ethyl)-2-cyano pyridine (or) 3-[2-(3-Chlorophenyl)–ethyl]–2–pyridine carbonitrile (Cyano compound) 31255-57-9 Antihistaminic
8-Chloro-5,6 dihydro(11H)-benzo[5,6] cyclohepta (1,2b) pyridine -11-one 31251-41-9
8 Chloro-11-[(N-methyl)-4-piperidylidene]-6, 11-dihydro-5H-benzo [5,6]cyclohepta (1,2b) pyridine (methyl loratadine) 38092-89-6
{3-[2-(3-Chlorophenyl)ethyl]pyridine-2-yl}-(1-methyl piperidine-4-yl) (methonal HCL) 119770-60-4
13 Mirabegron (R)-N-(4-nitrophenethyl)-2-hydroxy-2-phenylacetamide 521284-19-5 Over active bladder
(R)-2-(4-nitrophenethylamino)-1-phenylethanol.HCl 521284-21-9
(R)-2-(4-aminophenethylamino)-1-phenylethanol 521284-22-0
14 Prucalopride 1-(3-Methoxy propyl) piperidine-4-one 16771-85-0 Gatroprokinetic
1-(3-Methoxypropyl)-4-Piperidinamine 179474-79-4
15 Rifabutin 1-Isobutyl-4-piperidone 72544-16-2 Antibactrerial
16 Rivaroxaban 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone 446292-08-6 Antithromobotic
4-(4-((S)-5-(Aminomethyl)-2-oxooxazolidin-3-Yl) phenyl)morpholin-3-one HCl 898543-06-1
17 Ropivacaine (S)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide 27262-40-4 Anaesthesia 
18 Rupatadine Fumarate 3-Chloromethyl-5-methyl pyridine HCl 1007089-84-0 Antihistaminic
19 Selexipag 4-(Isopropylamino)butanol 42042-71-7 Antihypertensive
20 Tamsulosin R-(-)-5-(2-Amino-propyl)-2-methoxy-benzenesulfonamide 112101-81-2 in treatment of benign prostatic hypertrophy
5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide 106133-20-4
21 Trazadone [1,2,4]triazolo[4,3-a]pyridin-3-one 6969-71-7 Antidepressant 
"1-(3-chlorophenyl)-4-(3-chloropropyl) piperazine hydrochloride" 52605-52-4
22 Trimeperidine 1,2,5 trimethyl-4-Piperidone 7516-33-8 Antianalgesic
23 Vonoprazan Fumarate (VOF) 5-(2-Fluorophenyl)-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-carboxaldehyde 881677-11-8 Astric ulcer, duodenal ulcer and reflux esophagitis
24 Pemetrexed 4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-1H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)ETHYL] BENZOIC ACID 137281-39-1 Cancer
25 FELBAMATE 2-phenyl 1,3 propanediol 1570-95-2 Anticonvulsant (Epilepsy)
26 - N-(4-AMINO-2-CYANOPHENYL)-N,N-DIMETHYLMETHANIMIDAMIDE 194423-17-1