Vasudha Pharma Chem Limited is a trustworthy Losartan Potassium Manufacturers and Exporters in the pharmaceutical industry. Our company is engaged in developing and manufacturing of Active Pharmaceutical Ingredients (APIs), Pharmaceutical Intermediates, Piperidine Derivatives for catering to the domestic as well as international market.
Losartan Potassium API is a specific antagonist of the angiotensin II( receptor subtype AT1. Antagonism of the AT1 receptor and interference of association between AT1 and angiotensin II produces vasodilation and reduction of hypertension. Angiotensin is a peptide hormone that causes vasoconstriction & a subsequent raises blood pressure and also stimulates the release of aldosterone, hormones from the adrenal cortex. This antagonism has other downstream effects, including inhibition of platelet aggregation, a correlated antagonism of the thromboxane A2 receptor, and induction of peroxisome proliferator-activated receptor gamma (PPARγ) activity.
|Chemical Name||Potassium salt of 2-Butyl –4-Chloro-1-[2’ 1 H – Tetrazole –5-yl)[1,1’-biphenyl] 4-yl]emthyl]-1H-Imidazole –5 methanol|
|Storage Temp||-20°C Freezer|
|Solubility||Methanol (Slightly), Water (Slightly)|
|Application||A specific antagonist of the AT1 receptor with significant downstream effects|